Epidemiology of toxidermia in Dakar: Study of 200 cases

Background: Previous studies in Africa have shown severity of toxidermia with a risk mortality and mucosal synechia. Our objective was to study the epidemiological, clinical, etiological evolutionary aspects Dakar. Methods: A cross-sectional retrospective conducted at Department Dermatology Hospital Le Dantec from January 2001 December 2015. She identified all cases hospitalization this department. The diagnosis based on French criteria for drug accountability. Results: Two hundred were recorded. hospital frequency 9.2%. sex ratio 0.61. average age 33 years. Clinical forms bullous Stevens Johnson/Lyell 54% (n = 108), erythema multiforme 3% 6), fixed pigmented 2% 4). Mucosal involvement noted 56.5% 113). Visceral 15% 30) respiratory 24 SSJ/NET 6 DRESS. drugs antibiotics 38,7% 53), analgesics 15,3% 21), anti-comitials 13,1% 18), antiretrovirals 11,7% (n= 16), antituberculosis 9,5%% 13) medicinal plants 16). outcome favorable 62.5% 125). Death 12%. Conclusion: Toxidemia Dakar are characterized by predominance severe clinical young adults related infectious hydro electrolyte complications.